Disease: Memory Impairment, CTCAE 3.0
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VPS13A Q96RL7 vacuolar protein sorting 13 homolog A 9.3E-22 0.650 0.577
VCP P55072 valosin containing protein 1.00 0.469 0.923
VAMP1 P23763 vesicle associated membrane protein 1 3.9E-03 0.628 0.538
UBAC2 Q8NBM4 UBA domain containing 2 6.3E-03 0.638 0.654
TYROBP O43914 transmembrane immune signaling adaptor TYROBP 0.20 0.573 0.769
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SLC20A2 Q08357 solute carrier family 20 member 2 Transporter 0.97 0.638 0.577
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
RPS20 P60866 ribosomal protein S20 Nucleic acid binding 2.1E-02 0.610 0.692
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731